Θα ήθελα να ρωτήσω εαν κάποιος έχει ακούσει για το Padutin kallikrein και εάν ναι πού μπορώ να το βρώ.
https://www.ncbi.nlm.nih.gov/pubmed/495334 1979 Determination of various semen parameters and sex hormone levels in subfertile men during kallikrein therapy. Έρευνα σε 31 άντρες "Thus, systemic kallikrein administration induces significant changes of the pituitary-gonadal axis influencing spermatogenesis and epididymal sperm maturation."
https://www.ncbi.nlm.nih.gov/pubmed/1318646 1981 Possible effects of the kallikrein-kinin system on male reproductive functions. Clinical trials showed that systemic administration of kallikrein may be particularly useful for treatment of infertile men suffering from asthenozoospermia and/or oligozoospermia. During kallikrein therapy, the number of spermatozoa and both quantitative and qualitative sperm motility increased, and a significant improvement of the conception rate was achieved. An increased sperm number was also observed after application of the specific kininase II inhibitor captopril.
https://www.ncbi.nlm.nih.gov/pubmed/8243685 Efficacy of kallikrein in the treatment of oligozoospermia and asthenozoospermia: a double-blind trial. 1993 έρευνα σε 114 άντρες At the doses and for the duration given, our results were disappointing. The absence of a therapeutical effect, as evidenced in the present study may be due to the very low absorption rate of kallidinogenase after oral administration. Probably a much higher dose of kallidinogenase should be used to achieve a therapeutic affect.
https://www.ncbi.nlm.nih.gov/pubmed/1318646 1992 Possible effects of the kallikrein-kinin system on male reproductive functions Clinical trials showed that systemic administration of kallikrein may be particularly useful for treatment of infertile men suffering from asthenozoospermia and/or oligozoospermia. During kallikrein therapy, the number of spermatozoa and both quantitative and qualitative sperm motility increased, and a significant improvement of the conception rate was achieved. [δεν φαίνεται εδώ σε πόσους έγινε η έρευνα]
https://www.ncbi.nlm.nih.gov/pubmed/7818373 Penetration capacity of spermatozoa from patients with oligoasthenoteratozoospermia into bovine cervical mucus before and after therapy with kallikrein.
1994 έρευνα σε 45 άντρες Analysis of spermiograms and the penetration test were performed before and after 3 months of treatment. Neither of these techniques revealed significant alteration after treatment, nor was there a demonstrable success during the observation period in terms of pregnancy. Judging from these results, (1) kallikrein has no effect in patients with OAT syndrome and (2) the penetration test provides no additional information on the biological quality of ejaculate.